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Publications

Light-inducible molecular beacons for spatio-temporally highly defined activation. Rinne, JS; Kaminski, TP; Kubitscheck, U; Heckel, A; Chem Commun (Camb), 2013 May PubMed

Light-controlled tools. Brieke, C; Rohrbach, F; Gottschalk, A; Mayer, G; Heckel, A; Angew Chem Int Ed Engl, 2012 Aug PubMed

Ultrafast dynamics of a spiropyran in water. Kohl-Landgraf, J; Braun, M; Özçoban, C; Gonçalves, DP; Heckel, A; Wachtveitl, J; J Am Chem Soc, 2012 Aug PubMed

Caged glutathione - triggering protein interaction by light. Gatterdam, V; Stoess, T; Menge, C; Heckel, A; Tampé, R; Angew Chem Int Ed Engl, 2012 Apr PubMed

Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs. Wurm, JP; Griese, M; Bahr, U; Held, M; Heckel, A; Karas, M; Soppa, J; Wöhnert, J; RNA, 2012 Mar PubMed

Light-activatable molecular beacons with a caged loop sequence. Joshi, KB; Vlachos, A; Mikat, V; Deller, T; Heckel, A; Chem Commun (Camb), 2012 Mar PubMed

Caged glucosamine-6-phosphate for the light-control of riboswitch activity. Wulffen, B; Buff, MC; Pofahl, M; Mayer, G; Heckel, A; Photochem Photobiol Sci, 2012 Mar PubMed

Coumarin-caged dG for improved wavelength-selective uncaging of DNA. Menge, C; Heckel, A; Org Lett, 2011 Sep PubMed

Photon cascade with clip-on fluorophores. Friedrich, F; Heckel, A; Chemphyschem, 2011 Aug PubMed

Construction of a structurally defined double-stranded DNA catenane. Schmidt, TL; Heckel, A; Nano Lett, 2011 Apr PubMed

Wavelength-selective uncaging of dA and dC residues. Schäfer, F; Joshi, KB; Fichte, MA; Mack, T; Wachtveitl, J; Heckel, A; Org Lett, 2011 Mar PubMed

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA. Meyer, B; Wurm, JP; Kötter, P; Leisegang, MS; Schilling, V; Buchhaupt, M; Held, M; Bahr, U; Karas, M; Heckel, A; Bohnsack, MT; Wöhnert, J; Entian, KD; Nucleic Acids Res, 2011 Mar PubMed

Comparison of the duplex-destabilizing effects of nucleobase-caged oligonucleotides. Rodrigues-Correia, A; Koeppel, MB; Schäfer, F; Joshi, KB; Mack, T; Heckel, A; Anal Bioanal Chem, 2011 Jan PubMed

DNA minicircles connected via G-quadruplex interaction modules. Gonçalves, DP; Schmidt, TL; Koeppel, MB; Heckel, A; Small, 2010 Jun PubMed

Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates. Ackermann, D; Rasched, G; Verma, S; Schmidt, TL; Heckel, A; Famulok, M; Chem Commun (Camb), 2010 Jun PubMed

Prion protein amyloid formation involves structural rearrangements in the C-terminal domain. Kumar, J; Sreeramulu, S; Schmidt, TL; Richter, C; Vonck, J; Heckel, A; Glaubitz, C; Schwalbe, H; Chembiochem, 2010 Jun PubMed

A double-stranded DNA rotaxane. Ackermann, D; Schmidt, TL; Hannam, JS; Purohit, CS; Heckel, A; Famulok, M; Nat Nanotechnol, 2010 Jun PubMed

The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase. Wurm, JP; Meyer, B; Bahr, U; Held, M; Frolow, O; Kötter, P; Engels, JW; Heckel, A; Karas, M; Entian, KD; Wöhnert, J; Nucleic Acids Res, 2010 Apr PubMed

Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency. Buff, MC; Schäfer, F; Wulffen, B; Müller, J; Pötzsch, B; Heckel, A; Mayer, G; Nucleic Acids Res, 2010 Apr PubMed

Probing the limits of liquid droplet laser desorption mass spectrometry in the analysis of oligonucleotides and nucleic acids. Hoffmann, J; Schmidt, TL; Heckel, A; Brutschy, B; Rapid Commun Mass Spectrom, 2009 Jul PubMed

Pyrrole/imidazole-polyamide anchors for DNA tertiary interactions. Schmidt, TL; Heckel, A; Small, 2009 Jul PubMed

Structure-activity relationships of a caged thrombin binding DNA aptamer: insight gained from molecular dynamics simulation studies. Jayapal, P; Mayer, G; Heckel, A; Wennmohs, F; J Struct Biol, 2009 Jun PubMed

Differential regulation of protein subdomain activity with caged bivalent ligands. Mayer, G; Müller, J; Mack, T; Freitag, DF; Höver, T; Pötzsch, B; Heckel, A; Chembiochem, 2009 Mar PubMed

Completion of a Programmable DNA-Binding Small Molecule Library. Hsu, CF; Phillips, JW; Trauger, JW; Farkas, ME; Belitsky, JM; Heckel, A; Olenyuk, BZ; Puckett, JW; Wang, CC; Dervan, PB; Tetrahedron, 2007 Jul PubMed

Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema. Savaskan, NE; Heckel, A; Hahnen, E; Engelhorn, T; Doerfler, A; Ganslandt, O; Nimsky, C; Buchfelder, M; Eyüpoglu, IY; Nat Med, 2008 Jun PubMed

Nucleobase-caged phosphoramidites for oligonucleotide synthesis. Heckel, A; Curr Protoc Nucleic Acid Chem, 2007 Jun PubMed

Building objects from nucleic acids for a nanometer world. Heckel, A; Famulok, M; Biochimie, 2008 Jul PubMed

Binding of hairpin polyamides to DNA studied by fluorescence correlation spectroscopy for DNA nanoarchitectures. Nandi, CK; Parui, PP; Schmidt, TL; Heckel, A; Brutschy, B; Anal Bioanal Chem, 2008 Mar PubMed

DNA minicircles with gaps for versatile functionalization. Rasched, G; Ackermann, D; Schmidt, TL; Broekmann, P; Heckel, A; Famulok, M; Angew Chem Int Ed Engl, 2008 PubMed

Light-dependent RNA interference with nucleobase-caged siRNAs. Mikat, V; Heckel, A; RNA, 2007 Dec PubMed

Polyamide struts for DNA architectures. Schmidt, TL; Nandi, CK; Rasched, G; Parui, PP; Brutschy, B; Famulok, M; Heckel, A; Angew Chem Int Ed Engl, 2007 PubMed

Light-stimulated patterning of cells. Mayer, G; Heckel, A; Chembiochem, 2007 May PubMed

An anticoagulant with light-triggered antidote activity. Heckel, A; Buff, MC; Raddatz, MS; Müller, J; Pötzsch, B; Mayer, G; Angew Chem Int Ed Engl, 2006 Oct PubMed

Biologically active molecules with a "light switch". Mayer, G; Heckel, A; Angew Chem Int Ed Engl, 2006 Jul PubMed

Light-induced formation of G-quadruplex DNA secondary structures. Mayer, G; Kröck, L; Mikat, V; Engeser, M; Heckel, A; Chembiochem, 2005 Nov PubMed

A ribozyme for the aldol reaction. Fusz, S; Eisenführ, A; Srivatsan, SG; Heckel, A; Famulok, M; Chem Biol, 2005 Aug PubMed

Light regulation of aptamer activity: an anti-thrombin aptamer with caged thymidine nucleobases. Heckel, A; Mayer, G; J Am Chem Soc, 2005 Jan PubMed

Photoinduced transcription by using temporarily mismatched caged oligonucleotides. Kröck, L; Heckel, A; Angew Chem Int Ed Engl, 2005 Jan PubMed

A new DNA analogue with expanded size and scope. Heckel, A; Chembiochem, 2004 Jun PubMed

Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates. Edelson, BS; Best, TP; Olenyuk, B; Nickols, NG; Doss, RM; Foister, S; Heckel, A; Dervan, PB; Nucleic Acids Res, 2004 PubMed

U-pin polyamide motif for recognition of the DNA minor groove. Heckel, A; Dervan, PB; Chemistry, 2003 Jul PubMed

Preparation and characterization of TADDOLs immobilized on hydrophobic controlled-pore-glass silica gel and their use in enantioselective heterogeneous catalysis. Heckel, A; Seebach, D; Chemistry, 2002 Feb PubMed

TADDOLs, Their Derivatives, and TADDOL Analogues: Versatile Chiral Auxiliaries. Seebach, D; Beck, AK; Heckel, A; Angew Chem Int Ed Engl, 2001 Jan PubMed

Cover Picture. Seebach, D; Beck, AK; Heckel, A; Angew Chem Int Ed Engl, 2001 Jan PubMed

Immobilization of TADDOL with a High Degree of Loading on Porous Silica Gel and First Applications in Enantioselective Catalysis. Heckel, A; Seebach, D; Angew Chem Int Ed Engl, 2000 Jan PubMed