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Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response. Sharma, K; Vabulas, RM; Macek, B; Pinkert, S; Cox, J; Mann, M; Hartl, FU; Mol Cell Proteomics, 2012 Mar PubMed

Aberrant protein interactions in amyloid disease. Vabulas, RM; Hartl, FU; Cell Cycle, 2011 May PubMed

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication. Resenberger, UK; Harmeier, A; Woerner, AC; Goodman, JL; Müller, V; Krishnan, R; Vabulas, RM; Kretzschmar, HA; Lindquist, S; Hartl, FU; Multhaup, G; Winklhofer, KF; Tatzelt, J; EMBO J, 2011 May PubMed

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions. Olzscha, H; Schermann, SM; Woerner, AC; Pinkert, S; Hecht, MH; Tartaglia, GG; Vendruscolo, M; Hayer-Hartl, M; Hartl, FU; Vabulas, RM; Cell, 2011 Jan PubMed

Protein folding in the cytoplasm and the heat shock response. Vabulas, RM; Raychaudhuri, S; Hayer-Hartl, M; Hartl, FU; Cold Spring Harb Perspect Biol, 2010 Dec PubMed

Proteasome function and protein biosynthesis. Vabulas, RM; Curr Opin Clin Nutr Metab Care, 2007 Jan PubMed

A balance of protein synthesis and proteasome-dependent degradation determines the maintenance of LTP. Fonseca, R; Vabulas, RM; Hartl, FU; Bonhoeffer, T; Nägerl, UV; Neuron, 2006 Oct PubMed

Protein synthesis upon acute nutrient restriction relies on proteasome function. Vabulas, RM; Hartl, FU; Science, 2005 Dec PubMed

Heat shock proteins as ligands of toll-like receptors. Vabulas, RM; Wagner, H; Schild, H; Curr Top Microbiol Immunol, 2002 PubMed

Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection. Weighardt, H; Kaiser-Moore, S; Vabulas, RM; Kirschning, CJ; Wagner, H; Holzmann, B; J Immunol, 2002 Sep PubMed

CpG-DNA aided cross-presentation of soluble antigens by dendritic cells. Maurer, T; Heit, A; Hochrein, H; Ampenberger, F; O'Keeffe, M; Bauer, S; Lipford, GB; Vabulas, RM; Wagner, H; Eur J Immunol, 2002 Aug PubMed

Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Ahmad-Nejad, P; Häcker, H; Rutz, M; Bauer, S; Vabulas, RM; Wagner, H; Eur J Immunol, 2002 Jul PubMed

The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway. Vabulas, RM; Braedel, S; Hilf, N; Singh-Jasuja, H; Herter, S; Ahmad-Nejad, P; Kirschning, CJ; Da Costa, C; Rammensee, HG; Wagner, H; Schild, H; J Biol Chem, 2002 Jun PubMed

HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. Vabulas, RM; Ahmad-Nejad, P; Ghose, S; Kirschning, CJ; Issels, RD; Wagner, H; J Biol Chem, 2002 Apr PubMed

Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. Vabulas, RM; Ahmad-Nejad, P; da Costa, C; Miethke, T; Kirschning, CJ; Häcker, H; Wagner, H; J Biol Chem, 2001 Aug PubMed

Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins. Sparwasser, T; Vabulas, RM; Villmow, B; Lipford, GB; Wagner, H; Eur J Immunol, 2000 Dec PubMed

Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6. Häcker, H; Vabulas, RM; Takeuchi, O; Hoshino, K; Akira, S; Wagner, H; J Exp Med, 2000 Aug PubMed

CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses. Vabulas, RM; Pircher, H; Lipford, GB; Häcker, H; Wagner, H; J Immunol, 2000 Mar PubMed

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Sparwasser, T; Koch, ES; Vabulas, RM; Heeg, K; Lipford, GB; Ellwart, JW; Wagner, H; Eur J Immunol, 1998 Jun PubMed