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Solid-state NMR enhanced by dynamic nuclear polarization as a novel tool for ribosome structural biology. Gelis, I; Vitzthum, V; Dhimole, N; Caporini, MA; Schedlbauer, A; Carnevale, D; Connell, SR; Fucini, P; Bodenhausen, G; J Biomol NMR, 2013 May PubMed

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Ratje, AH; Loerke, J; Mikolajka, A; Brünner, M; Hildebrand, PW; Starosta, AL; Dönhöfer, A; Connell, SR; Fucini, P; Mielke, T; Whitford, PC; Onuchic, JN; Yu, Y; Sanbonmatsu, KY; Hartmann, RK; Penczek, PA; Wilson, DN; Spahn, CM; Nature, 2010 Dec PubMed

Mass spectrometry defines the stoichiometry of ribosomal stalk complexes across the phylogenetic tree. Gordiyenko, Y; Videler, H; Zhou, M; McKay, AR; Fucini, P; Biegel, E; Müller, V; Robinson, CV; Mol Cell Proteomics, 2010 Aug PubMed

PSRP1 is not a ribosomal protein, but a ribosome-binding factor that is recycled by the ribosome-recycling factor (RRF) and elongation factor G (EF-G). Sharma, MR; Dönhöfer, A; Barat, C; Marquez, V; Datta, PP; Fucini, P; Wilson, DN; Agrawal, RK; J Biol Chem, 2010 Feb PubMed

Probing side-chain dynamics of a ribosome-bound nascent chain using methyl NMR spectroscopy. Hsu, ST; Cabrita, LD; Fucini, P; Christodoulou, J; Dobson, CM; J Am Chem Soc, 2009 Jun PubMed

Structure, dynamics and folding of an immunoglobulin domain of the gelation factor (ABP-120) from Dictyostelium discoideum. Hsu, ST; Cabrita, LD; Fucini, P; Dobson, CM; Christodoulou, J; J Mol Biol, 2009 May PubMed

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Connell, SR; Topf, M; Qin, Y; Wilson, DN; Mielke, T; Fucini, P; Nierhaus, KH; Spahn, CM; Nat Struct Mol Biol, 2008 Sep PubMed

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning. Wilson, DN; Schluenzen, F; Harms, JM; Starosta, AL; Connell, SR; Fucini, P; Proc Natl Acad Sci U S A, 2008 Sep PubMed

Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Harms, JM; Wilson, DN; Schluenzen, F; Connell, SR; Stachelhaus, T; Zaborowska, Z; Spahn, CM; Fucini, P; Mol Cell, 2008 Apr PubMed

Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins. Sharma, MR; Wilson, DN; Datta, PP; Barat, C; Schluenzen, F; Fucini, P; Agrawal, RK; Proc Natl Acad Sci U S A, 2007 Dec PubMed

Structural aspects of RbfA action during small ribosomal subunit assembly. Datta, PP; Wilson, DN; Kawazoe, M; Swami, NK; Kaminishi, T; Sharma, MR; Booth, TM; Takemoto, C; Fucini, P; Yokoyama, S; Agrawal, RK; Mol Cell, 2007 Nov PubMed

Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy. Hsu, ST; Fucini, P; Cabrita, LD; Launay, H; Dobson, CM; Christodoulou, J; Proc Natl Acad Sci U S A, 2007 Oct PubMed

A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction. Kaminishi, T; Wilson, DN; Takemoto, C; Harms, JM; Kawazoe, M; Schluenzen, F; Hanawa-Suetsugu, K; Shirouzu, M; Fucini, P; Yokoyama, S; Structure, 2007 Mar PubMed

Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Connell, SR; Takemoto, C; Wilson, DN; Wang, H; Murayama, K; Terada, T; Shirouzu, M; Rost, M; Schüler, M; Giesebrecht, J; Dabrowski, M; Mielke, T; Fucini, P; Yokoyama, S; Spahn, CM; Mol Cell, 2007 Mar PubMed

The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Schluenzen, F; Takemoto, C; Wilson, DN; Kaminishi, T; Harms, JM; Hanawa-Suetsugu, K; Szaflarski, W; Kawazoe, M; Shirouzu, M; Shirouzo, M; Nierhaus, KH; Yokoyama, S; Fucini, P; Nat Struct Mol Biol, 2006 Oct PubMed

Species-specific antibiotic-ribosome interactions: implications for drug development. Wilson, DN; Harms, JM; Nierhaus, KH; Schlünzen, F; Fucini, P; Biol Chem, 2005 Dec PubMed

The binding mode of the trigger factor on the ribosome: implications for protein folding and SRP interaction. Schlünzen, F; Wilson, DN; Tian, P; Harms, JM; McInnes, SJ; Hansen, HA; Albrecht, R; Buerger, J; Wilbanks, SM; Fucini, P; Structure, 2005 Nov PubMed

Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria. Ilag, LL; Videler, H; McKay, AR; Sobott, F; Fucini, P; Nierhaus, KH; Robinson, CV; Proc Natl Acad Sci U S A, 2005 Jun PubMed

Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly. Sharma, MR; Barat, C; Wilson, DN; Booth, TM; Kawazoe, M; Hori-Takemoto, C; Shirouzu, M; Yokoyama, S; Fucini, P; Agrawal, RK; Mol Cell, 2005 Apr PubMed

High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome. Giavalisco, P; Wilson, D; Kreitler, T; Lehrach, H; Klose, J; Gobom, J; Fucini, P; Plant Mol Biol, 2005 Mar PubMed

Nanoflow liquid chromatography coupled to matrix-assisted laser desorption/ionization mass spectrometry: sample preparation, data analysis, and application to the analysis of complex peptide mixtures. Mirgorodskaya, E; Braeuer, C; Fucini, P; Lehrach, H; Gobom, J; Proteomics, 2005 Feb PubMed

X-ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit. Wilson, DN; Schluenzen, F; Harms, JM; Yoshida, T; Ohkubo, T; Albrecht, R; Buerger, J; Kobayashi, Y; Fucini, P; EMBO J, 2005 Jan PubMed

Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Schlünzen, F; Pyetan, E; Fucini, P; Yonath, A; Harms, JM; Mol Microbiol, 2004 Dec PubMed

Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes. Christodoulou, J; Larsson, G; Fucini, P; Connell, SR; Pertinhez, TA; Hanson, CL; Redfield, C; Nierhaus, KH; Robinson, CV; Schleucher, J; Dobson, CM; Proc Natl Acad Sci U S A, 2004 Jul PubMed

Three-dimensional structures of translating ribosomes by Cryo-EM. Gilbert, RJ; Fucini, P; Connell, S; Fuller, SD; Nierhaus, KH; Robinson, CV; Dobson, CM; Stuart, DI; Mol Cell, 2004 Apr PubMed

Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin. Harms, JM; Schlünzen, F; Fucini, P; Bartels, H; Yonath, A; BMC Biol, 2004 PubMed

Dissecting the ribosomal inhibition mechanisms of edeine and pactamycin: the universally conserved residues G693 and C795 regulate P-site RNA binding. Dinos, G; Wilson, DN; Teraoka, Y; Szaflarski, W; Fucini, P; Kalpaxis, D; Nierhaus, KH; Mol Cell, 2004 Jan PubMed

Ribosomal crystallography: peptide bond formation and its inhibition. Bashan, A; Zarivach, R; Schluenzen, F; Agmon, I; Harms, J; Auerbach, T; Baram, D; Berisio, R; Bartels, H; Hansen, HA; Fucini, P; Wilson, D; Peretz, M; Kessler, M; Yonath, A; Biopolymers, 2003 Sep PubMed

Structural insight into the antibiotic action of telithromycin against resistant mutants. Berisio, R; Harms, J; Schluenzen, F; Zarivach, R; Hansen, HA; Fucini, P; Yonath, A; J Bacteriol, 2003 Jul PubMed

On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes. Derived on 20 October 2002 at the 28th FEBS Meeting in Istanbul. Agmon, I; Auerbach, T; Baram, D; Bartels, H; Bashan, A; Berisio, R; Fucini, P; Hansen, HA; Harms, J; Kessler, M; Peretz, M; Schluenzen, F; Yonath, A; Zarivach, R; Eur J Biochem, 2003 Jun PubMed

Dissociation of intact Escherichia coli ribosomes in a mass spectrometer. Evidence for conformational change in a ribosome elongation factor G complex. Hanson, CL; Fucini, P; Ilag, LL; Nierhaus, KH; Robinson, CV; J Biol Chem, 2003 Jan PubMed

Detection and selective dissociation of intact ribosomes in a mass spectrometer. Rostom, AA; Fucini, P; Benjamin, DR; Juenemann, R; Nierhaus, KH; Hartl, FU; Dobson, CM; Robinson, CV; Proc Natl Acad Sci U S A, 2000 May PubMed

Molecular architecture of the rod domain of the Dictyostelium gelation factor (ABP120). Fucini, P; Köppel, B; Schleicher, M; Lustig, A; Holak, TA; Müller, R; Stewart, M; Noegel, AA; J Mol Biol, 1999 Sep PubMed

Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod. McCoy, AJ; Fucini, P; Noegel, AA; Stewart, M; Nat Struct Biol, 1999 Sep PubMed

Location of the binding site of the mannose-specific lectin comitin on F-actin. Fulgenzi, G; Graciotti, L; Granata, AL; Corsi, A; Fucini, P; Noegel, AA; Kent, HM; Stewart, M; J Mol Biol, 1998 Dec PubMed

Crystallization and preliminary X-Ray diffraction characterization of a dimerizing fragment of the rod domain of the Dictyostelium gelation factor (ABP-120). Fucini, P; McCoy, AJ; Gomez-Ortiz, M; Schleicher, M; Noegel, AA; Stewart, M; J Struct Biol, 1997 Nov PubMed

The repeating segments of the F-actin cross-linking gelation factor (ABP-120) have an immunoglobulin-like fold. Fucini, P; Renner, C; Herberhold, C; Noegel, AA; Holak, TA; Nat Struct Biol, 1997 Mar PubMed

Linking microfilaments to intracellular membranes: the actin-binding and vesicle-associated protein comitin exhibits a mannose-specific lectin activity. Jung, E; Fucini, P; Stewart, M; Noegel, AA; Schleicher, M; EMBO J, 1996 Mar PubMed