Research Groups


Publications of Anja Bremm (Results: 13)


Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome.
Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A, Kaulich M PubMed
Mar 2019 Volume: 8 Issue: Pages:

Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase.
Nature chemical biology
Fottner M, Brunner AD, Bittl V, Horn-Ghetko D, Jussupow A, Kaila VRI, Bremm A, Lang K PubMed
03 2019 Volume: 15 Issue: 3 Pages: 276-284

Ubiquitin chain diversity at a glance.
Journal of cell science
Akutsu M, Dikic I, Bremm A PubMed
Mar 2016 Volume: 129 Issue: 5 Pages: 875-80

Cezanne regulates E2F1-dependent HIF2α expression.
Journal of cell science
Moniz S, Bandarra D, Biddlestone J, Campbell KJ, Komander D, Bremm A, Rocha S PubMed
Aug 2015 Volume: 128 Issue: 16 Pages: 3082-93

Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner.
EMBO reports
Bremm A, Moniz S, Mader J, Rocha S, Komander D PubMed
Dec 2014 Volume: 15 Issue: 12 Pages: 1268-77

DUBs counteract parkin for efficient mitophagy.
The EMBO journal
Dikic I, Bremm A PubMed
Nov 2014 Volume: 33 Issue: 21 Pages: 2442-3

Synthesis and analysis of K11-linked ubiquitin chains.
Methods in molecular biology (Clifton, N.J.)
Bremm A, Komander D PubMed
2012 Volume: 832 Issue: Pages: 219-28

Emerging roles for Lys11-linked polyubiquitin in cellular regulation.
Trends in biochemical sciences
Bremm A, Komander D PubMed
Jul 2011 Volume: 36 Issue: 7 Pages: 355-63

A further case of Dop-ing in bacterial pupylation.
EMBO reports
Bremm A, Komander D PubMed
Oct 2010 Volume: 11 Issue: 10 Pages: 722-3

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne.
Nature structural & molecular biology
Bremm A, Freund SM, Komander D PubMed
Aug 2010 Volume: 17 Issue: 8 Pages: 939-47

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain.
Nature structural & molecular biology
Kulathu Y, Akutsu M, Bremm A, Hofmann K, Komander D PubMed
Dec 2009 Volume: 16 Issue: 12 Pages: 1328-30

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.
Genome research
Markson G, Kiel C, Hyde R, Brown S, Charalabous P, Bremm A, Semple J, Woodsmith J, Duley S, Salehi-Ashtiani K, Vidal M, Komander D, Serrano L, Lehner P, Sanderson CM PubMed
Oct 2009 Volume: 19 Issue: 10 Pages: 1905-11

Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations.
Cancer research
Bremm A, Walch A, Fuchs M, Mages J, Duyster J, Keller G, Hermannstädter C, Becker KF, Rauser S, Langer R, von Weyhern CH, Höfler H, Luber B PubMed
Feb 2008 Volume: 68 Issue: 3 Pages: 707-14