Research Groups


Publications of Ernst Stelzer (Results: 166)


A deterministic genotyping workflow reduces waste of transgenic individuals by two-thirds.
Scientific reports
Strobl F, Stelzer EHK PubMed
Jul 2021 Volume: 11 Issue: 1 Pages: 15325

Non-invasive analysis of pancreas organoids in synthetic hydrogels defines material-cell interactions and luminal composition.
Biomaterials science
Jung N, Moreth T, Stelzer EHK, Pampaloni F, Windbergs M PubMed
Jul 2021 Volume: Issue: Pages:

Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis.
BMC biology
Hof L, Moreth T, Koch M, Liebisch T, Kurtz M, Tarnick J, Lissek SM, Verstegen MMA, van der Laan LJW, Huch M, Matthäus F, Stelzer EHK, Pampaloni F PubMed
02 2021 Volume: 19 Issue: 1 Pages: 37

Cell fate clusters in ICM organoids arise from cell fate heredity and division: a modelling approach.
Scientific reports
Liebisch T, Drusko A, Mathew B, Stelzer EHK, Fischer SC, Matthäus F PubMed
12 2020 Volume: 10 Issue: 1 Pages: 22405

p63 uses a switch-like mechanism to set the threshold for induction of apoptosis.
Nature chemical biology
Gebel J, Tuppi M, Chaikuad A, Hötte K, Schröder M, Schulz L, Löhr F, Gutfreund N, Finke F, Henrich E, Mezhyrova J, Lehnert R, Pampaloni F, Hummer G, Stelzer EHK, Knapp S, Dötsch V PubMed
10 2020 Volume: 16 Issue: 10 Pages: 1078-1086

The transition from local to global patterns governs the differentiation of mouse blastocysts.
PloS one
Fischer SC, Corujo-Simon E, Lilao-Garzon J, Stelzer EHK, Muñoz-Descalzo S PubMed
2020 Volume: 15 Issue: 5 Pages: e0233030

Measuring Stepwise Binding of Thermally Fluctuating Particles to Cell Membranes without Fluorescence.
Biophysical journal
Rohrbach A, Meyer T, Stelzer EHK, Kress H PubMed
04 2020 Volume: 118 Issue: 8 Pages: 1850-1860

Early developmental plasticity of lateral roots in response to asymmetric water availability.
Nature plants
von Wangenheim D, Banda J, Schmitz A, Boland J, Bishopp A, Maizel A, Stelzer EHK, Bennett M PubMed
02 2020 Volume: 6 Issue: 2 Pages: 73-77

Ultra-thin fluorocarbon foils optimise multiscale imaging of three-dimensional native and optically cleared specimens.
Scientific reports
Hötte K, Koch M, Hof L, Tuppi M, Moreth T, Verstegen MMA, van der Laan LJW, Stelzer EHK, Pampaloni F PubMed
11 2019 Volume: 9 Issue: 1 Pages: 17292

An ancestral apical brain region contributes to the central complex under the control of in the beetle .
He B, Buescher M, Farnworth MS, Strobl F, Stelzer EH, Koniszewski ND, Muehlen D, Bucher G PubMed
10 2019 Volume: 8 Issue: Pages:

A GABAergic and peptidergic sleep neuron as a locomotion stop neuron with compartmentalized Ca2+ dynamics.
Nature communications
Steuer Costa W, Van der Auwera P, Glock C, Liewald JF, Bach M, Schüler C, Wabnig S, Oranth A, Masurat F, Bringmann H, Schoofs L, Stelzer EHK, Fischer SC, Gottschalk A PubMed
09 2019 Volume: 10 Issue: 1 Pages: 4095

Success Rate of Intra-articular Sacroiliac Joint Injection: Fluoroscopy vs Ultrasound Guidance-A Cadaveric Study.
Pain medicine (Malden, Mass.)
Stelzer W, Stelzer D, Stelzer E, Sammer A, Aichner E, Braune M, Schneider BJ, Duller C, Feigl G PubMed
10 2019 Volume: 20 Issue: 10 Pages: 1890-1897

Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury.
Kidney international
Poluzzi C, Nastase MV, Zeng-Brouwers J, Roedig H, Hsieh LT, Michaelis JB, Buhl EM, Rezende F, Manavski Y, Bleich A, Boor P, Brandes RP, Pfeilschifter J, Stelzer EHK, Münch C, Dikic I, Brandts C, Iozzo RV, Wygrecka M, Schaefer L PubMed
03 2019 Volume: 95 Issue: 3 Pages: 540-562

E-cadherin, actin, microtubules and FAK dominate different spheroid formation phases and important elements of tissue integrity.
Biology open
Smyrek I, Mathew B, Fischer SC, Lissek SM, Becker S, Stelzer EHK PubMed
Jan 2019 Volume: 8 Issue: 1 Pages:

Mouse ICM Organoids Reveal Three-Dimensional Cell Fate Clustering.
Biophysical journal
Mathew B, Muñoz-Descalzo S, Corujo-Simon E, Schröter C, Stelzer EHK, Fischer SC PubMed
01 2019 Volume: 116 Issue: 1 Pages: 127-141

The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1.
The Journal of cell biology
Hofbauer HF, Gecht M, Fischer SC, Seybert A, Frangakis AS, Stelzer EHK, Covino R, Hummer G, Ernst R PubMed
09 2018 Volume: 217 Issue: 9 Pages: 3109-3126

A universal vector concept for a direct genotyping of transgenic organisms and a systematic creation of homozygous lines.
Strobl F, Anderl A, Stelzer EH PubMed
03 2018 Volume: 7 Issue: Pages:

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.
Nature structural & molecular biology
Tuppi M, Kehrloesser S, Coutandin DW, Rossi V, Luh LM, Strubel A, Hötte K, Hoffmeister M, Schäfer B, De Oliveira T, Greten F, Stelzer EHK, Knapp S, De Felici M, Behrends C, Klinger FG, Dötsch V PubMed
03 2018 Volume: 25 Issue: 3 Pages: 261-269

Changes in the allocation of endogenous strigolactone improve plant biomass production on phosphate-poor soils.
The New phytologist
Liu G, Pfeifer J, de Brito Francisco R, Emonet A, Stirnemann M, Gübeli C, Hutter O, Sasse J, Mattheyer C, Stelzer E, Walter A, Martinoia E, Borghi L PubMed
01 2018 Volume: 217 Issue: 2 Pages: 784-798

Non-lethal genotyping of Tribolium castaneum adults using genomic DNA extracted from wing tissue.
PloS one
Strobl F, Ross JA, Stelzer EHK PubMed
2017 Volume: 12 Issue: 8 Pages: e0182564

Light Sheet-based Fluorescence Microscopy of Living or Fixed and Stained Tribolium castaneum Embryos.
Journal of visualized experiments : JoVE
Strobl F, Klees S, Stelzer EHK PubMed
04 2017 Volume: Issue: 122 Pages:

Endogenous AJAP1 associates with the cytoskeleton and attenuates angiogenesis in endothelial cells.
Biology open
Hötte K, Smyrek I, Starzinski-Powitz A, Stelzer EHK PubMed
Jun 2017 Volume: 6 Issue: 6 Pages: 723-731

Improving your four-dimensional image: traveling through a decade of light-sheet-based fluorescence microscopy research.
Nature protocols
Strobl F, Schmitz A, Stelzer EHK PubMed
Jun 2017 Volume: 12 Issue: 6 Pages: 1103-1109

csiLSFM combines light-sheet fluorescence microscopy and coherent structured illumination for a lateral resolution below 100 nm.
Proceedings of the National Academy of Sciences of the United States of America
Chang BJ, Perez Meza VD, Stelzer EHK PubMed
05 2017 Volume: 114 Issue: 19 Pages: 4869-4874

Three-Dimensional Live Imaging of Filamentous Fungi with Light Sheet-Based Fluorescence Microscopy (LSFM).
Methods in molecular biology (Clifton, N.J.)
Pampaloni F, Knuppertz L, Hamann A, Osiewacz HD, Stelzer EHK PubMed
2017 Volume: 1563 Issue: Pages: 19-31

A Novel Cellular Spheroid-Based Autophagy Screen Applying Live Fluorescence Microscopy Identifies Nonactin as a Strong Inducer of Autophagosomal Turnover.
SLAS discovery : advancing life sciences R & D
Pampaloni F, Mayer B, Kabat Vel-Job K, Ansari N, Hötte K, Kögel D, Stelzer EHK PubMed
06 2017 Volume: 22 Issue: 5 Pages: 558-570

Quantitative three-dimensional evaluation of immunofluorescence staining for large whole mount spheroids with light sheet microscopy.
Biomedical optics express
Smyrek I, Stelzer EH PubMed
Feb 2017 Volume: 8 Issue: 2 Pages: 484-499

Multiscale image analysis reveals structural heterogeneity of the cell microenvironment in homotypic spheroids.
Scientific reports
Schmitz A, Fischer SC, Mattheyer C, Pampaloni F, Stelzer EH PubMed
03 2017 Volume: 7 Issue: Pages: 43693

Long-term fluorescence live imaging of Tribolium castaneum embryos: principles, resources, scientific challenges and the comparative approach.
Current opinion in insect science
Strobl F, Stelzer EH PubMed
12 2016 Volume: 18 Issue: Pages: 17-26

Alternative exon usage creates novel transcript variants of tumor suppressor SHREW-1 gene with differential tissue expression profile.
Biology open
Klemmt PA, Resch E, Smyrek I, Engels K, Stelzer EH, Starzinski-Powitz A PubMed
Nov 2016 Volume: 5 Issue: 11 Pages: 1607-1619

Optimal 2D-SIM reconstruction by two filtering steps with Richardson-Lucy deconvolution.
Scientific reports
Perez V, Chang BJ, Stelzer EH PubMed
11 2016 Volume: 6 Issue: Pages: 37149

Identifying the necrotic zone boundary in tumour spheroids with pair-correlation functions.
Journal of the Royal Society, Interface
Dini S, Binder BJ, Fischer SC, Mattheyer C, Schmitz A, Stelzer EH, Bean NG, Green JE PubMed
10 2016 Volume: 13 Issue: 123 Pages:

Hsp90 Is Involved in the Regulation of Cytosolic Precursor Protein Abundance in Tomato.
Molecular plant
Tillmann B, Röth S, Bublak D, Sommer M, Stelzer EH, Scharf KD, Schleiff E PubMed
Jul 2015 Volume: 8 Issue: 7 Pages: 1128

A 3-D cell culture system to study epithelia functions using microcarriers.
Jakob PH, Kehrer J, Flood P, Wiegel C, Haselmann U, Meissner M, Stelzer EH, Reynaud EG PubMed
Oct 2016 Volume: 68 Issue: 5 Pages: 1813-25

Rules and Self-Organizing Properties of Post-embryonic Plant Organ Cell Division Patterns.
Current biology : CB
von Wangenheim D, Fangerau J, Schmitz A, Smith RS, Leitte H, Stelzer EH, Maizel A PubMed
Feb 2016 Volume: 26 Issue: 4 Pages: 439-49

Live imaging of Tribolium castaneum embryonic development using light-sheet-based fluorescence microscopy.
Nature protocols
Strobl F, Schmitz A, Stelzer EH PubMed
Oct 2015 Volume: 10 Issue: 10 Pages: 1486-507

Erratum to: light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues.
Cell and tissue research
Pampaloni F, Chang BJ, Stelzer EH PubMed
Oct 2015 Volume: 362 Issue: 1 Pages: 265

Robust and automated three-dimensional segmentation of densely packed cell nuclei in different biological specimens with Lines-of-Sight decomposition.
BMC bioinformatics
Mathew B, Schmitz A, Muñoz-Descalzo S, Ansari N, Pampaloni F, Stelzer EH, Fischer SC PubMed
Jun 2015 Volume: 16 Issue: Pages: 187

Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids.
BMC cancer
Giannattasio A, Weil S, Kloess S, Ansari N, Stelzer EH, Cerwenka A, Steinle A, Koehl U, Koch J PubMed
May 2015 Volume: 15 Issue: Pages: 351

Light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues.
Cell and tissue research
Pampaloni F, Chang BJ, Stelzer EH PubMed
Apr 2015 Volume: 360 Issue: 1 Pages: 129-41

A Photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase.
Chembiochem : a European journal of chemical biology
Nollmann FI, Heinrich AK, Brachmann AO, Morisseau C, Mukherjee K, Casanova-Torres ÁM, Strobl F, Kleinhans D, Kinski S, Schultz K, Beeton ML, Kaiser M, Chu YY, Phan Ke L, Thanwisai A, Bozhüyük KA, Chantratita N, Götz F, Waterfield NR, Vilcinskas A, Stelzer EH, Goodrich-Blair H, Hammock BD, Bode HB PubMed
Mar 2015 Volume: 16 Issue: 5 Pages: 766-71

Hsp90 is involved in the regulation of cytosolic precursor protein abundance in tomato.
Molecular plant
Tillmann B, Röth S, Bublak D, Sommer M, Stelzer EH, Scharf KD, Schleiff E PubMed
Feb 2015 Volume: 8 Issue: 2 Pages: 228-41

Lateral assembly of N-cadherin drives tissue integrity by stabilizing adherens junctions.
Journal of the Royal Society, Interface
Garg S, Fischer SC, Schuman EM, Stelzer EH PubMed
Mar 2015 Volume: 12 Issue: 104 Pages: 20141055

Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A.
Biology open
Ingold E, Vom Berg-Maurer CM, Burckhardt CJ, Lehnherr A, Rieder P, Keller PJ, Stelzer EH, Greber UF, Neuhauss SC, Gesemann M PubMed
Jan 2015 Volume: 4 Issue: 2 Pages: 146-54

Light-sheet fluorescence microscopy for quantitative biology.
Nature methods
Stelzer EH PubMed
Jan 2015 Volume: 12 Issue: 1 Pages: 23-6

Better imaging through chemistry.
Stelzer EH PubMed
Dec 2014 Volume: 159 Issue: 6 Pages: 1243-6

Live spheroid formation recorded with light sheet-based fluorescence microscopy.
Methods in molecular biology (Clifton, N.J.)
Pampaloni F, Richa R, Ansari N, Stelzer EH PubMed
2015 Volume: 1251 Issue: Pages: 43-57

Invited review article: Advanced light microscopy for biological space research.
The Review of scientific instruments
De Vos WH, Beghuin D, Schwarz CJ, Jones DB, van Loon JJ, Bereiter-Hahn J, Stelzer EH PubMed
Oct 2014 Volume: 85 Issue: 10 Pages: 101101

"I connect with the ringleader:" health professionals' perspectives on promoting the sexual health of adolescent males.
Research in nursing & health
Garcia CM, Ptak SJ, Stelzer EB, Harwood EM, Brady SS PubMed
Dec 2014 Volume: 37 Issue: 6 Pages: 454-65

Hsp90 is involved in the regulation of cytosolic precursor protein abundance in tomato.
Molecular plant
Tillmann B, Röth S, Bublak D, Sommer M, Stelzer EH, Scharf KD, Schleiff E PubMed
Oct 2014 Volume: Issue: Pages:

Trans-Golgi network localized small GTPase RabA1d is involved in cell plate formation and oscillatory root hair growth.
BMC plant biology
Berson T, von Wangenheim D, Takáč T, Šamajová O, Rosero A, Ovečka M, Komis G, Stelzer EH, Šamaj J PubMed
Sep 2014 Volume: 14 Issue: Pages: 252

Tissue-culture light sheet fluorescence microscopy (TC-LSFM) allows long-term imaging of three-dimensional cell cultures under controlled conditions.
Integrative biology : quantitative biosciences from nano to macro
Pampaloni F, Berge U, Marmaras A, Horvath P, Kroschewski R, Stelzer EH PubMed
Oct 2014 Volume: 6 Issue: 10 Pages: 988-98

Quantifying the autophagy-triggering effects of drugs in cell spheroids with live fluorescence microscopy.
Methods in molecular biology (Clifton, N.J.)
Ansari N, Hardung S, Hötte K, Rakel S, Antonietti P, Kögel D, Stelzer EH, Pampaloni F PubMed
2014 Volume: 1165 Issue: Pages: 19-29

Non-invasive long-term fluorescence live imaging of Tribolium castaneum embryos.
Development (Cambridge, England)
Strobl F, Stelzer EH PubMed
Jun 2014 Volume: 141 Issue: 11 Pages: 2331-8

Identification of autophagy as a longevity-assurance mechanism in the aging model Podospora anserina.
Knuppertz L, Hamann A, Pampaloni F, Stelzer E, Osiewacz HD PubMed
May 2014 Volume: 10 Issue: 5 Pages: 822-34

Live imaging and quantitative analysis of gastrulation in mouse embryos using light-sheet microscopy and 3D tracking tools.
Nature protocols
Ichikawa T, Nakazato K, Keller PJ, Kajiura-Kobayashi H, Stelzer EH, Mochizuki A, Nonaka S PubMed
Mar 2014 Volume: 9 Issue: 3 Pages: 575-85

3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions.
Experimental cell research
Wenzel C, Riefke B, Gründemann S, Krebs A, Christian S, Prinz F, Osterland M, Golfier S, Räse S, Ansari N, Esner M, Bickle M, Pampaloni F, Mattheyer C, Stelzer EH, Parczyk K, Prechtl S, Steigemann P PubMed
Apr 2014 Volume: 323 Issue: 1 Pages: 131-143

A spatial accommodation by neighboring cells is required for organ initiation in Arabidopsis.
Science (New York, N.Y.)
Vermeer JE, von Wangenheim D, Barberon M, Lee Y, Stelzer EH, Maizel A, Geldner N PubMed
Jan 2014 Volume: 343 Issue: 6167 Pages: 178-83

Imaging MDCK cysts with a single (selective) plane illumination microscope.
Cold Spring Harbor protocols
Swoger J, Pampaloni F, Stelzer EH PubMed
Jan 2014 Volume: 2014 Issue: 1 Pages: 114-8

Imaging cellular spheroids with a single (selective) plane illumination microscope.
Cold Spring Harbor protocols
Swoger J, Pampaloni F, Stelzer EH PubMed
Jan 2014 Volume: 2014 Issue: 1 Pages: 106-13

Light-sheet-based fluorescence microscopy for three-dimensional imaging of biological samples.
Cold Spring Harbor protocols
Swoger J, Pampaloni F, Stelzer EH PubMed
Jan 2014 Volume: 2014 Issue: 1 Pages: 1-8

Role of N-cadherin cis and trans interfaces in the dynamics of adherens junctions in living cells.
PloS one
Bunse S, Garg S, Junek S, Vogel D, Ansari N, Stelzer EH, Schuman E PubMed
2013 Volume: 8 Issue: 12 Pages: e81517

Live imaging of Arabidopsis development.
Methods in molecular biology (Clifton, N.J.)
von Wangenheim D, Daum G, Lohmann JU, Stelzer EK, Maizel A PubMed
2014 Volume: 1062 Issue: Pages: 539-50

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Archives of toxicology
Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, H... PubMed
Aug 2013 Volume: 87 Issue: 8 Pages: 1315-530

Live imaging of whole mouse embryos during gastrulation: migration analyses of epiblast and mesodermal cells.
PloS one
Ichikawa T, Nakazato K, Keller PJ, Kajiura-Kobayashi H, Stelzer EH, Mochizuki A, Nonaka S PubMed
2013 Volume: 8 Issue: 7 Pages: e64506

An auxin transport mechanism restricts positive orthogravitropism in lateral roots.
Current biology : CB
Rosquete MR, von Wangenheim D, Marhavý P, Barbez E, Stelzer EH, Benková E, Maizel A, Kleine-Vehn J PubMed
May 2013 Volume: 23 Issue: 9 Pages: 817-22

Lateral root morphogenesis is dependent on the mechanical properties of the overlaying tissues.
Proceedings of the National Academy of Sciences of the United States of America
Lucas M, Kenobi K, von Wangenheim D, Voβ U, Swarup K, De Smet I, Van Damme D, Lawrence T, Péret B, Moscardi E, Barbeau D, Godin C, Salt D, Guyomarc'h S, Stelzer EH, Maizel A, Laplaze L, Bennett MJ PubMed
Mar 2013 Volume: 110 Issue: 13 Pages: 5229-34

High-resolution deep imaging of live cellular spheroids with light-sheet-based fluorescence microscopy.
Cell and tissue research
Pampaloni F, Ansari N, Stelzer EH PubMed
Apr 2013 Volume: 352 Issue: 1 Pages: 161-77

Quantitative 3D cell-based assay performed with cellular spheroids and fluorescence microscopy.
Methods in cell biology
Ansari N, Müller S, Stelzer EH, Pampaloni F PubMed
2013 Volume: 113 Issue: Pages: 295-309

Three-dimensional Fluorescence Lifetime Imaging with a Single Plane Illumination Microscope provides an improved signal to noise ratio.
Optics express
Greger K, Neetz MJ, Reynaud EG, Stelzer EH PubMed
Oct 2011 Volume: 19 Issue: 21 Pages: 20743-50

Digital scanned laser light-sheet fluorescence microscopy (DSLM) of zebrafish and Drosophila embryonic development.
Cold Spring Harbor protocols
Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EH PubMed
Oct 2011 Volume: 2011 Issue: 10 Pages: 1235-43

Viscoelastic response of contractile filament bundles.
Physical review. E, Statistical, nonlinear, and soft matter physics
Besser A, Colombelli J, Stelzer EH, Schwarz US PubMed
May 2011 Volume: 83 Issue: 5 Pt 1 Pages: 051902

High-resolution live imaging of plant growth in near physiological bright conditions using light sheet fluorescence microscopy.
The Plant journal : for cell and molecular biology
Maizel A, von Wangenheim D, Federici F, Haseloff J, Stelzer EH PubMed
Oct 2011 Volume: 68 Issue: 2 Pages: 377-85

A novel laser nanosurgery approach supports de novo Golgi biogenesis in mammalian cells.
Journal of cell science
Tängemo C, Ronchi P, Colombelli J, Haselmann U, Simpson JC, Antony C, Stelzer EH, Pepperkok R, Reynaud EG PubMed
Mar 2011 Volume: 124 Issue: Pt 6 Pages: 978-87

Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage.
Journal of cell science
Roukos V, Kinkhabwala A, Colombelli J, Kotsantis P, Taraviras S, Nishitani H, Stelzer E, Bastiaens P, Lygerou Z PubMed
Feb 2011 Volume: 124 Issue: Pt 3 Pages: 422-34

ImFCS: a software for imaging FCS data analysis and visualization.
Optics express
Sankaran J, Shi X, Ho LY, Stelzer EH, Wohland T PubMed
Dec 2010 Volume: 18 Issue: 25 Pages: 25468-81

Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos.
PloS one
Redemann S, Pecreaux J, Goehring NW, Khairy K, Stelzer EH, Hyman AA, Howard J PubMed
Aug 2010 Volume: 5 Issue: 8 Pages: e12301

Madin-Darby canine kidney cells are increased in aerobic glycolysis when cultured on flat and stiff collagen-coated surfaces rather than in physiological 3-D cultures.
Pampaloni F, Stelzer EH, Leicht S, Marcello M PubMed
Oct 2010 Volume: 10 Issue: 19 Pages: 3394-413

Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy.
Nature methods
Keller PJ, Schmidt AD, Santella A, Khairy K, Bao Z, Wittbrodt J, Stelzer EH PubMed
Aug 2010 Volume: 7 Issue: 8 Pages: 637-42

Single plane illumination fluorescence correlation spectroscopy (SPIM-FCS) probes inhomogeneous three-dimensional environments.
Optics express
Wohland T, Shi X, Sankaran J, Stelzer EH PubMed
May 2010 Volume: 18 Issue: 10 Pages: 10627-41

Digital scanned laser light sheet fluorescence microscopy.
Cold Spring Harbor protocols
Keller PJ, Stelzer EH PubMed
May 2010 Volume: 2010 Issue: 5 Pages: pdb.top78

Three-dimensional cell cultures in toxicology.
Biotechnology & genetic engineering reviews
Pampaloni F, Stelzer E PubMed
2010 Volume: 26 Issue: Pages: 117-38

Nlcam modulates midline convergence during anterior neural plate morphogenesis.
Developmental biology
Brown KE, Keller PJ, Ramialison M, Rembold M, Stelzer EH, Loosli F, Wittbrodt J PubMed
Mar 2010 Volume: 339 Issue: 1 Pages: 14-25

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.
Nature structural & molecular biology
Timinszky G, Till S, Hassa PO, Hothorn M, Kustatscher G, Nijmeijer B, Colombelli J, Altmeyer M, Stelzer EH, Scheffzek K, Hottiger MO, Ladurner AG PubMed
Sep 2009 Volume: 16 Issue: 9 Pages: 923-9

Three-dimensional tissue models for drug discovery and toxicology.
Recent patents on biotechnology
Pampaloni F, Stelzer EH, Masotti A PubMed
2009 Volume: 3 Issue: 2 Pages: 103-17

Light sheet-based fluorescence microscopy: more dimensions, more photons, and less photodamage.
HFSP journal
Reynaud EG, Krzic U, Greger K, Stelzer EH PubMed
Oct 2008 Volume: 2 Issue: 5 Pages: 266-75

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization.
Journal of cell science
Colombelli J, Besser A, Kress H, Reynaud EG, Girard P, Caussinus E, Haselmann U, Small JV, Schwarz US, Stelzer EH PubMed
May 2009 Volume: 122 Issue: Pt 10 Pages: 1665-79

Quantitative in vivo imaging of entire embryos with Digital Scanned Laser Light Sheet Fluorescence Microscopy.
Current opinion in neurobiology
Keller PJ, Stelzer EH PubMed
Dec 2008 Volume: 18 Issue: 6 Pages: 624-32

A correlative light and electron microscopy method based on laser micropatterning and etching.
Methods in molecular biology (Clifton, N.J.)
Colombelli J, Tängemo C, Haselman U, Antony C, Stelzer EH, Pepperkok R, Reynaud EG PubMed
2008 Volume: 457 Issue: Pages: 203-13

Mechanism of phototaxis in marine zooplankton.
Jékely G, Colombelli J, Hausen H, Guy K, Stelzer E, Nédélec F, Arendt D PubMed
Nov 2008 Volume: 456 Issue: 7220 Pages: 395-9

Detection of deformable objects in 3D images using Markov-Chain Monte Carlo and spherical harmonics.
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Khairy K, Reynaud E, Stelzer E PubMed
2008 Volume: 11 Issue: Pt 2 Pages: 1075-82

Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy.
Science (New York, N.Y.)
Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EH PubMed
Nov 2008 Volume: 322 Issue: 5904 Pages: 1065-9

The SpoMBe pathway drives membrane bending necessary for cytokinesis and spore formation in yeast meiosis.
The EMBO journal
Maier P, Rathfelder N, Maeder CI, Colombelli J, Stelzer EH, Knop M PubMed
Sep 2008 Volume: 27 Issue: 18 Pages: 2363-74

In vivo imaging of the inflammatory receptor CD40 after cerebral ischemia using a fluorescent antibody.
Klohs J, Gräfe M, Graf K, Steinbrink J, Dietrich T, Stibenz D, Bahmani P, Kronenberg G, Harms C, Endres M, Lindauer U, Greger K, Stelzer EH, Dirnagl U, Wunder A PubMed
Oct 2008 Volume: 39 Issue: 10 Pages: 2845-52

Three-dimensional microtubule behavior in Xenopus egg extracts reveals four dynamic states and state-dependent elastic properties.
Biophysical journal
Keller PJ, Pampaloni F, Lattanzi G, Stelzer EH PubMed
Aug 2008 Volume: 95 Issue: 3 Pages: 1474-86

Resolution improvement by nonconfocal theta microscopy.
Optics letters
Lindek S, Stelzer EH PubMed
Nov 1999 Volume: 24 Issue: 21 Pages: 1505-7

Optical levitation of absorbing particles with a nominally Gaussian laser beam.
Optics letters
Huisken J, Stelzer EH PubMed
Jul 2002 Volume: 27 Issue: 14 Pages: 1223-5

Three-dimensional preparation and imaging reveal intrinsic microtubule properties.
Nature methods
Keller PJ, Pampaloni F, Stelzer EH PubMed
Oct 2007 Volume: 4 Issue: 10 Pages: 843-6

The third dimension bridges the gap between cell culture and live tissue.
Nature reviews. Molecular cell biology
Pampaloni F, Reynaud EG, Stelzer EH PubMed
Oct 2007 Volume: 8 Issue: 10 Pages: 839-45

Filopodia act as phagocytic tentacles and pull with discrete steps and a load-dependent velocity.
Proceedings of the National Academy of Sciences of the United States of America
Kress H, Stelzer EH, Holzer D, Buss F, Griffiths G, Rohrbach A PubMed
Jul 2007 Volume: 104 Issue: 28 Pages: 11633-8

Lateral modulation boosts image quality in single plane illumination fluorescence microscopy.
Optics letters
Breuninger T, Greger K, Stelzer EH PubMed
Jul 2007 Volume: 32 Issue: 13 Pages: 1938-40

Investigating relaxation processes in cells and developing organisms: from cell ablation to cytoskeleton nanosurgery.
Methods in cell biology
Colombelli J, Reynaud EG, Stelzer EH PubMed
2007 Volume: 82 Issue: Pages: 267-91

Multi-view image fusion improves resolution in three-dimensional microscopy.
Optics express
Swoger J, Verveer P, Greger K, Huisken J, Stelzer EH PubMed
Jun 2007 Volume: 15 Issue: 13 Pages: 8029-42

Basic building units and properties of a fluorescence single plane illumination microscope.
The Review of scientific instruments
Greger K, Swoger J, Stelzer EH PubMed
Feb 2007 Volume: 78 Issue: 2 Pages: 023705

Three-dimensional laser microsurgery in light-sheet based microscopy (SPIM).
Optics express
Engelbrecht CJ, Greger K, Reynaud EG, Krzic U, Colombelli J, Stelzer EH PubMed
May 2007 Volume: 15 Issue: 10 Pages: 6420-30

Three-dimensional optical manipulation using four collimated intersecting laser beams.
Optics express
Huisken J, Swoger J, Stelzer EH PubMed
Apr 2007 Volume: 15 Issue: 8 Pages: 4921-8

High-resolution three-dimensional imaging of large specimens with light sheet-based microscopy.
Nature methods
Verveer PJ, Swoger J, Pampaloni F, Greger K, Marcello M, Stelzer EH PubMed
Apr 2007 Volume: 4 Issue: 4 Pages: 311-3

Dynamic organization of the actin cytoskeleton during meiosis and spore formation in budding yeast.
Traffic (Copenhagen, Denmark)
Taxis C, Maeder C, Reber S, Rathfelder N, Miura K, Greger K, Stelzer EH, Knop M PubMed
Dec 2006 Volume: 7 Issue: 12 Pages: 1628-42

Dynein-mediated pulling forces drive rapid mitotic spindle elongation in Ustilago maydis.
The EMBO journal
Fink G, Schuchardt I, Colombelli J, Stelzer E, Steinberg G PubMed
Oct 2006 Volume: 25 Issue: 20 Pages: 4897-908

Interferometric tracking of optically trapped probes behind structured surfaces: A phase correction method.
Applied optics
Seitz PC, Stelzer EH, Rohrbach A PubMed
Oct 2006 Volume: 45 Issue: 28 Pages: 7309-15

Nud1p, the yeast homolog of Centriolin, regulates spindle pole body inheritance in meiosis.
The EMBO journal
Gordon O, Taxis C, Keller PJ, Benjak A, Stelzer EH, Simchen G, Knop M PubMed
Aug 2006 Volume: 25 Issue: 16 Pages: 3856-68

[Laser nanosurgery in cell biology].
Medecine sciences : M/S
Colombelli J, Pepperkok R, Stelzer EH, Reynaud EG PubMed
Volume: 22 Issue: 6-7 Pages: 651-8

Resolution enhancement in a light-sheet-based microscope (SPIM).
Optics letters
Engelbrecht CJ, Stelzer EH PubMed
May 2006 Volume: 31 Issue: 10 Pages: 1477-9

Life sciences require the third dimension.
Current opinion in cell biology
Keller PJ, Pampaloni F, Stelzer EH PubMed
Feb 2006 Volume: 18 Issue: 1 Pages: 117-24

Spore number control and breeding in Saccharomyces cerevisiae: a key role for a self-organizing system.
The Journal of cell biology
Taxis C, Keller P, Kavagiou Z, Jensen LJ, Colombelli J, Bork P, Stelzer EH, Knop M PubMed
Nov 2005 Volume: 171 Issue: 4 Pages: 627-40

In vivo selective cytoskeleton dynamics quantification in interphase cells induced by pulsed ultraviolet laser nanosurgery.
Traffic (Copenhagen, Denmark)
Colombelli J, Reynaud EG, Rietdorf J, Pepperkok R, Stelzer EH PubMed
Dec 2005 Volume: 6 Issue: 12 Pages: 1093-102

Control of relative radiation pressure in optical traps: application to phagocytic membrane binding studies.
Physical review. E, Statistical, nonlinear, and soft matter physics
Kress H, Stelzer EH, Griffiths G, Rohrbach A PubMed
Jun 2005 Volume: 71 Issue: 6 Pt 1 Pages: 061927

Three-dimensional bead position histograms reveal single-molecule nanomechanics.
Physical review. E, Statistical, nonlinear, and soft matter physics
Becker NB, Altmann SM, Scholz T, Hörber JK, Stelzer EH, Rohrbach A PubMed
Feb 2005 Volume: 71 Issue: 2 Pt 1 Pages: 021907

Stable chromosomal units determine the spatial and temporal organization of DNA replication.
Journal of cell science
Sadoni N, Cardoso MC, Stelzer EH, Leonhardt H, Zink D PubMed
Oct 2004 Volume: 117 Issue: Pt 22 Pages: 5353-65

Mechanical properties of single motor molecules studied by three-dimensional thermal force probing in optical tweezers.
Chemphyschem : a European journal of chemical physics and physical chemistry
Jeney S, Stelzer EH, Grubmüller H, Florin EL PubMed
Aug 2004 Volume: 5 Issue: 8 Pages: 1150-8

Optical sectioning deep inside live embryos by selective plane illumination microscopy.
Science (New York, N.Y.)
Huisken J, Swoger J, Del Bene F, Wittbrodt J, Stelzer EH PubMed
Aug 2004 Volume: 305 Issue: 5686 Pages: 1007-9

Multiple imaging axis microscopy improves resolution for thick-sample applications.
Optics letters
Swoger J, Huisken J, Stelzer EH PubMed
Sep 2003 Volume: 28 Issue: 18 Pages: 1654-6

Dynamic organization of the actin system in the motile cells of Dictyostelium.
Journal of muscle research and cell motility
Bretschneider T, Jonkman J, Köhler J, Medalia O, Barisic K, Weber I, Stelzer EH, Baumeister W, Gerisch G PubMed
2002 Volume: 23 Issue: 7-8 Pages: 639-49

The distribution of active force generators controls mitotic spindle position.
Science (New York, N.Y.)
Grill SW, Howard J, Schäffer E, Stelzer EH, Hyman AA PubMed
Jul 2003 Volume: 301 Issue: 5632 Pages: 518-21

Albumin-based drug delivery as novel therapeutic approach for rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Wunder A, Müller-Ladner U, Stelzer EH, Funk J, Neumann E, Stehle G, Pap T, Sinn H, Gay S, Fiehn C PubMed
May 2003 Volume: 170 Issue: 9 Pages: 4793-801

Three-dimensional tracking of small spheres in focused laser beams: influence of the detection angular aperture.
Optics letters
Rohrbach A, Kress H, Stelzer EH PubMed
Mar 2003 Volume: 28 Issue: 6 Pages: 411-3

Resolution in optical microscopy.
Methods in enzymology
Jonkman JE, Swoger J, Kress H, Rohrbach A, Stelzer EH PubMed
2003 Volume: 360 Issue: Pages: 416-46

Visualizing chromatin and chromosomes in living cells.
Methods (San Diego, Calif.)
Zink D, Sadoni N, Stelzer E PubMed
Jan 2003 Volume: 29 Issue: 1 Pages: 42-50

Optical scanning holography as a technique for high-resolution three-dimensional biological microscopy.
Journal of the Optical Society of America. A, Optics, image science, and vision
Swoger J, Martínez-Corral M, Huisken J, Stelzer EH PubMed
Sep 2002 Volume: 19 Issue: 9 Pages: 1910-8

Beyond the diffraction limit?
Stelzer EH PubMed
Jun 2002 Volume: 417 Issue: 6891 Pages: 806-7

Trapping forces, force constants, and potential depths for dielectric spheres in the presence of spherical aberrations.
Applied optics
Rohrbach A, Stelzer EH PubMed
May 2002 Volume: 41 Issue: 13 Pages: 2494-507

Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons.
Molecular biology of the cell
Rolls MM, Hall DH, Victor M, Stelzer EH, Rapoport TA PubMed
May 2002 Volume: 13 Issue: 5 Pages: 1778-91

Tailoring the axial shape of the point spread function using the Toraldo concept.
Optics express
Martinez-Corral M, Caballero M, Stelzer EH, Swoger J PubMed
Jan 2002 Volume: 10 Issue: 1 Pages: 98-103

Spatial partitioning of secretory cargo from Golgi resident proteins in live cells.
BMC cell biology
White J, Keller P, Stelzer EH PubMed
2001 Volume: 2 Issue: Pages: 19

Spindle positioning during the asymmetric first cell division of Caenorhabditis elegans embryos.
Novartis Foundation symposium
Gönczy P, Grill S, Stelzer EH, Kirkham M, Hyman AA PubMed
2001 Volume: 237 Issue: Pages: 164-75; discussion 176-81

Large-scale chromatin fibers of living cells display a discontinuous functional organization.
Sadoni N, Sullivan KF, Weinzierl P, Stelzer EH, Zink D PubMed
Apr 2001 Volume: 110 Issue: 1 Pages: 39-51

Quantitative ER <--> Golgi transport kinetics and protein separation upon Golgi exit revealed by vesicular integral membrane protein 36 dynamics in live cells.
Molecular biology of the cell
Dahm T, White J, Grill S, Füllekrug J, Stelzer EH PubMed
May 2001 Volume: 12 Issue: 5 Pages: 1481-98

Optical trapping of dielectric particles in arbitrary fields.
Journal of the Optical Society of America. A, Optics, image science, and vision
Rohrbach A, Stelzer EH PubMed
Apr 2001 Volume: 18 Issue: 4 Pages: 839-53

Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo.
Grill SW, Gönczy P, Stelzer EH, Hyman AA PubMed
Feb 2001 Volume: 409 Issue: 6820 Pages: 630-3

Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells.
The Journal of cell biology
White J, Johannes L, Mallard F, Girod A, Grill S, Reinsch S, Keller P, Tzschaschel B, Echard A, Goud B, Stelzer EH PubMed
Nov 1999 Volume: 147 Issue: 4 Pages: 743-60

The BioImage Database Project: organizing multidimensional biological images in an object-relational database.
Journal of structural biology
Carazo JM, Stelzer EH PubMed
Volume: 125 Issue: 2-3 Pages: 97-102

Three-dimensional high-resolution particle tracking for optical tweezers by forward scattered light.
Microscopy research and technique
Pralle A, Prummer M, Florin EL, Stelzer EH, Hörber JK PubMed
Mar 1999 Volume: 44 Issue: 5 Pages: 378-86

Photobleaching GFP reveals protein dynamics inside live cells.
Trends in cell biology
White J, Stelzer E PubMed
Feb 1999 Volume: 9 Issue: 2 Pages: 61-5

Recycling of golgi-resident glycosyltransferases through the ER reveals a novel pathway and provides an explanation for nocodazole-induced Golgi scattering.
The Journal of cell biology
Storrie B, White J, Röttger S, Stelzer EH, Suganuma T, Nilsson T PubMed
Dec 1998 Volume: 143 Issue: 6 Pages: 1505-21

Organising multi-dimensional biological image information: the BioImage Database.
Nucleic acids research
Carazo JM, Stelzer EH, Engel A, Fita I, Henn C, Machtynger J, McNeil P, Shotton DM, Chagoyen M, de Alarcón PA, Fritsch R, Heymann JB, Kalko S, Pittet JJ, Rodriguez-Tomé P, Boudier T PubMed
Jan 1999 Volume: 27 Issue: 1 Pages: 280-3

Structure and dynamics of human interphase chromosome territories in vivo.
Human genetics
Zink D, Cremer T, Saffrich R, Fischer R, Trendelenburg MF, Ansorge W, Stelzer EH PubMed
Feb 1998 Volume: 102 Issue: 2 Pages: 241-51

Photonic force microscope based on optical tweezers and two-photon excitation for biological applications.
Journal of structural biology
Florin EL, Pralle A, Hörber JK, Stelzer EH PubMed
Jul 1997 Volume: 119 Issue: 2 Pages: 202-11

Confocal theta fluorescence microscopy with annular apertures.
Applied optics
Lindek S, Cremer C, Stelzer EH PubMed
Jan 1996 Volume: 35 Issue: 1 Pages: 126-30

Fluorescence of coumarins and xanthenes after two-photon absorption with a pulsed titanium-sapphire laser.
Applied optics
Fischer A, Cremer C, Stelzer EH PubMed
Apr 1995 Volume: 34 Issue: 12 Pages: 1989-2003

Application of confocal laser microscopy and three-dimensional Voronoi diagrams for volume and surface estimates of interphase chromosomes.
Journal of microscopy
Eils R, Bertin E, Saracoglu K, Rinke B, Schröck E, Parazza F, Usson Y, Robert-Nicoud M, Stelzer EH, Chassery JM PubMed
Feb 1995 Volume: 177 Issue: Pt 2 Pages: 150-61

The intracellular mobility of a viral membrane glycoprotein measured by confocal microscope fluorescence recovery after photobleaching.
Journal of cell science
Storrie B, Pepperkok R, Stelzer EH, Kreis TE PubMed
May 1994 Volume: 107 ( Pt 5) Issue: Pages: 1309-19

Confocal microscopy with an increased detection aperture: type-B 4Pi confocal microscopy.
Optics letters
Hell SW, Stelzer EH, Lindek S, Cremer C PubMed
Feb 1994 Volume: 19 Issue: 3 Pages: 222

Differences of size and shape of active and inactive X-chromosome domains in human amniotic fluid cell nuclei.
Microscopy research and technique
Bischoff A, Albers J, Kharboush I, Stelzer E, Cremer T, Cremer C PubMed
May 1993 Volume: 25 Issue: 1 Pages: 68-77

Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts.
The Journal of cell biology
Verde F, Dogterom M, Stelzer E, Karsenti E, Leibler S PubMed
Sep 1992 Volume: 118 Issue: 5 Pages: 1097-108

Apical and basal Forssman antigen in MDCK II cells: a morphological and quantitative study.
European journal of cell biology
Butor C, Stelzer EH, Sonnenberg A, Davoust J PubMed
Dec 1991 Volume: 56 Issue: 2 Pages: 269-85

Hypervariable C-terminal domain of rab proteins acts as a targeting signal.
Chavrier P, Gorvel JP, Stelzer E, Simons K, Gruenberg J, Zerial M PubMed
Oct 1991 Volume: 353 Issue: 6346 Pages: 769-72

Confocal fluorescence microscopy in modern cell biology.
Seminars in cell biology
Stelzer EH, Wacker I, De Mey JR PubMed
Jun 1991 Volume: 2 Issue: 3 Pages: 145-52

The three-dimensional architecture of the mitotic spindle, analyzed by confocal fluorescence and electron microscopy.
Journal of electron microscopy technique
Merdes A, Stelzer EH, De Mey J PubMed
May 1991 Volume: 18 Issue: 1 Pages: 61-73

Regulation of microtubule dynamics and nucleation during polarization in MDCK II cells.
The Journal of cell biology
Bré MH, Pepperkok R, Hill AM, Levilliers N, Ansorge W, Stelzer EH, Karsenti E PubMed
Dec 1990 Volume: 111 Issue: 6 Pt 2 Pages: 3013-21

Distribution of chromosome 18 and X centric heterochromatin in the interphase nucleus of cultured human cells.
Experimental cell research
Popp S, Scholl HP, Loos P, Jauch A, Stelzer E, Cremer C, Cremer T PubMed
Jul 1990 Volume: 189 Issue: 1 Pages: 1-12

[The prognostic value of the acoustic stimulation test for fetal wellbeing and neonatal status. Controlled acoustic stimulation of the fetus in the last pregnancy trimester].
Zeitschrift fur Geburtshilfe und Perinatologie
Stelzer E, Dederichs M, Wolff F PubMed
Volume: 194 Issue: 3 Pages: 104-9

Unique geometry of actin-membrane anchorage sites in avian gizzard smooth muscle cells.
Journal of cell science
Draeger A, Stelzer EH, Herzog M, Small JV PubMed
Dec 1989 Volume: 94 ( Pt 4) Issue: Pages: 703-11

The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium.
The Journal of cell biology
Bacallao R, Antony C, Dotti C, Karsenti E, Stelzer EH, Simons K PubMed
Dec 1989 Volume: 109 Issue: 6 Pt 1 Pages: 2817-32

An antibody against secretogranin I (chromogranin B) is packaged into secretory granules.
The Journal of cell biology
Rosa P, Weiss U, Pepperkok R, Ansorge W, Niehrs C, Stelzer EH, Huttner WB PubMed
Jul 1989 Volume: 109 Issue: 1 Pages: 17-34

Preservation of biological specimens for observation in a confocal fluorescence microscope and operational principles of confocal fluorescence microscopy.
Methods in cell biology
Bacallao R, Stelzer EH PubMed
1989 Volume: 31 Issue: Pages: 437-52

Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells.
The Journal of cell biology
van Meer G, Stelzer EH, Wijnaendts-van-Resandt RW, Simons K PubMed
Oct 1987 Volume: 105 Issue: 4 Pages: 1623-35