Research Groups


Publications of Amparo Acker-Palmer (Results: 55)


Molecular neuroscience community shares perspectives.
Gura T, Acker-Palmer A, Kolodkin A, Meijers R, Mizuno N, Seiradake E, Tessier-Lavigne M PubMed
Nov 2022 Volume: 110 Issue: 22 Pages: 3656-3660

Expansion microscopy of mouse brain organotypic slice cultures to study protein distribution.
STAR protocols
Bissen D, Kracht MK, Foss F, Acker-Palmer A PubMed
Sep 2022 Volume: 3 Issue: 3 Pages: 101507

Vascular Regulation of Developmental Neurogenesis.
Frontiers in cell and developmental biology
Vogenstahl J, Parrilla M, Acker-Palmer A, Segarra M PubMed
2022 Volume: 10 Issue: Pages: 890852

The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner.
Cell reports
Luck R, Karakatsani A, Shah B, Schermann G, Adler H, Kupke J, Tisch N, Jeong HW, Back MK, Hetsch F, D'Errico A, De Palma M, Wiedtke E, Grimm D, Acker-Palmer A, von Engelhardt J, Adams RH, Augustin HG, Ruiz de Almodóvar C PubMed
Aug 2021 Volume: 36 Issue: 7 Pages: 109522

Neurovascular crosstalk coordinates the central nervous system development.
Current opinion in neurobiology
Peguera B, Segarra M, Acker-Palmer A PubMed
Aug 2021 Volume: 69 Issue: Pages: 202-213

EphrinB2 and GRIP1 stabilize mushroom spines during denervation-induced homeostatic plasticity.
Cell reports
Bissen D, Kracht MK, Foss F, Hofmann J, Acker-Palmer A PubMed
Mar 2021 Volume: 34 Issue: 13 Pages: 108923

EVL regulates VEGF receptor-2 internalization and signaling in developmental angiogenesis.
EMBO reports
Zink J, Frye M, Frömel T, Carlantoni C, John D, Schreier D, Weigert A, Laban H, Salinas G, Stingl H, Günther L, Popp R, Hu J, Vanhollebeke B, Schmidt H, Acker-Palmer A, Renné T, Fleming I, Benz PM PubMed
Feb 2021 Volume: 22 Issue: 2 Pages: e48961

Blood-Brain Barrier Dynamics to Maintain Brain Homeostasis.
Trends in neurosciences
Segarra M, Aburto MR, Acker-Palmer A PubMed
May 2021 Volume: 44 Issue: 5 Pages: 393-405

Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC.
Cell reports
Volz C, Breid S, Selenz C, Zaplatina A, Golfmann K, Meder L, Dietlein F, Borchmann S, Chatterjee S, Siobal M, Schöttle J, Florin A, Koker M, Nill M, Ozretić L, Uhlenbrock N, Smith S, Büttner R, Miao H, Wang B, Reinhardt HC, Rauh D, Hallek M, Acker-Palmer A, Heukamp LC, Ullrich RT PubMed
Apr 2020 Volume: 31 Issue: 4 Pages: 107568

Carotid body type I cells engage flavoprotein and Pin1 for oxygen sensing.
American journal of physiology. Cell physiology
Bernardini A, Wolf A, Brockmeier U, Riffkin H, Metzen E, Acker-Palmer A, Fandrey J, Acker H PubMed
Apr 2020 Volume: 318 Issue: 4 Pages: C719-C731

p120-catenin-dependent collective brain infiltration by glioma cell networks.
Nature cell biology
Gritsenko PG, Atlasy N, Dieteren CEJ, Navis AC, Venhuizen JH, Veelken C, Schubert D, Acker-Palmer A, Westerman BA, Wurdinger T, Leenders W, Wesseling P, Stunnenberg HG, Friedl P PubMed
Jan 2020 Volume: 22 Issue: 1 Pages: 97-107

EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development.
Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, Segarra M, Ruiz de Almodóvar C, Acker-Palmer A PubMed
Dec 2019 Volume: 8 Issue: Pages:

VEGF/VEGFR2 signaling regulates hippocampal axon branching during development.
Luck R, Urban S, Karakatsani A, Harde E, Sambandan S, Nicholson L, Haverkamp S, Mann R, Martin-Villalba A, Schuman EM, Acker-Palmer A, Ruiz de Almodóvar C PubMed
Dec 2019 Volume: 8 Issue: Pages:

Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.
Pan C, Schoppe O, Parra-Damas A, Cai R, Todorov MI, Gondi G, von Neubeck B, Böğürcü-Seidel N, Seidel S, Sleiman K, Veltkamp C, Förstera B, Mai H, Rong Z, Trompak O, Ghasemigharagoz A, Reimer MA, Cuesta AM, Coronel J, Jeremias I, Saur D, Acker-Palmer A, Acker T, Garvalov BK, Menze B, Zeidler R, Ertürk A PubMed
Dec 2019 Volume: 179 Issue: 7 Pages: 1661-1676.e19

Neurovascular Interactions in the Nervous System.
Annual review of cell and developmental biology
Segarra M, Aburto MR, Hefendehl J, Acker-Palmer A PubMed
Oct 2019 Volume: 35 Issue: Pages: 615-635

AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking.
Cellular and molecular life sciences : CMLS
Bissen D, Foss F, Acker-Palmer A PubMed
Jun 2019 Volume: 76 Issue: 11 Pages: 2133-2169

Loss of the Chr16p11.2 ASD candidate gene leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model.
Molecular autism
Haslinger D, Waltes R, Yousaf A, Lindlar S, Schneider I, Lim CK, Tsai MM, Garvalov BK, Acker-Palmer A, Krezdorn N, Rotter B, Acker T, Guillemin GJ, Fulda S, Freitag CM, Chiocchetti AG PubMed
2018 Volume: 9 Issue: Pages: 56

Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system.
Science (New York, N.Y.)
Segarra M, Aburto MR, Cop F, Llaó-Cid C, Härtl R, Damm M, Bethani I, Parrilla M, Husainie D, Schänzer A, Schlierbach H, Acker T, Mohr L, Torres-Masjoan L, Ritter M, Acker-Palmer A PubMed
Aug 2018 Volume: 361 Issue: 6404 Pages:

Disruption of the Microglial ADP Receptor P2Y Enhances Adult Hippocampal Neurogenesis.
Frontiers in cellular neuroscience
Stefani J, Tschesnokowa O, Parrilla M, Robaye B, Boeynaems JM, Acker-Palmer A, Zimmermann H, Gampe K PubMed
2018 Volume: 12 Issue: Pages: 134

PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFα.
Cancer research
Dopeso H, Jiao HK, Cuesta AM, Henze AT, Jurida L, Kracht M, Acker-Palmer A, Garvalov BK, Acker T PubMed
Apr 2018 Volume: 78 Issue: 7 Pages: 1805-1819

Aβ42 oligomers impair the bioenergetic activity in hippocampal synaptosomes derived from APP-KO mice.
Biological chemistry
Beckert B, Acker-Palmer A, Volknandt W PubMed
Apr 2018 Volume: 399 Issue: 5 Pages: 453-465

GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse.
Cell reports
Pfennig S, Foss F, Bissen D, Harde E, Treeck JC, Segarra M, Acker-Palmer A PubMed
Oct 2017 Volume: 21 Issue: 1 Pages: 84-96

Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.
Acta neuropathologica
Syed YA, Zhao C, Mahad D, Möbius W, Altmann F, Foss F, González GA, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJM, Nave KA, Kotter MRN PubMed
Jul 2017 Volume: 134 Issue: 1 Pages: 167-168

APP Deletion Accounts for Age-Dependent Changes in the Bioenergetic Metabolism and in Hyperphosphorylated CaMKII at Stimulated Hippocampal Presynaptic Active Zones.
Frontiers in synaptic neuroscience
Laßek M, Weingarten J, Wegner M, Neupärtl M, Array TN, Harde E, Beckert B, Golghalyani V, Ackermann J, Koch I, Müller UC, Karas M, Acker-Palmer A, Volknandt W PubMed
2017 Volume: 9 Issue: Pages: 1

FAM222B Is Not a Likely Novel Candidate Gene for Cerebral Cavernous Malformations.
Molecular syndromology
Spiegler S, Kirchmaier B, Rath M, Korenke GC, Tetzlaff F, van de Vorst M, Neveling K, Acker-Palmer A, Kuss AW, Gilissen C, Fischer A, Schulte-Merker S, Felbor U PubMed
Jul 2016 Volume: 7 Issue: 3 Pages: 144-52

Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.
Acta neuropathologica
Syed YA, Zhao C, Mahad D, Möbius W, Altmann F, Foss F, González GA, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJ, Nave KA, Kotter MR PubMed
Jul 2016 Volume: 132 Issue: 1 Pages: 157

APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone.
PLoS computational biology
Laßek M, Weingarten J, Wegner M, Mueller BF, Rohmer M, Baeumlisberger D, Arrey TN, Hick M, Ackermann J, Acker-Palmer A, Koch I, Müller U, Karas M, Volknandt W PubMed
Apr 2016 Volume: 12 Issue: 4 Pages: e1004832

Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.
Acta neuropathologica
Syed YA, Zhao C, Mahad D, Möbius W, Altmann F, Foss F, González GA, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJM, Nave KA, Kotter MRN PubMed
Feb 2016 Volume: 131 Issue: 2 Pages: 281-298

Measurement of ROS Levels and Membrane Potential Dynamics in the Intact Carotid Body Ex Vivo.
Advances in experimental medicine and biology
Bernardini A, Brockmeier U, Metzen E, Berchner-Pfannschmidt U, Harde E, Acker-Palmer A, Papkovsky D, Acker H, Fandrey J PubMed
2015 Volume: 860 Issue: Pages: 55-9

14-3-3ζ coordinates adipogenesis of visceral fat.
Nature communications
Lim GE, Albrecht T, Piske M, Sarai K, Lee JTC, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD PubMed
Jul 2015 Volume: 6 Issue: Pages: 7671

A vascular perspective on neuronal migration.
Mechanisms of development
Segarra M, Kirchmaier BC, Acker-Palmer A PubMed
Nov 2015 Volume: 138 Pt 1 Issue: Pages: 17-25

Regional Specializations of the PAZ Proteomes Derived from Mouse Hippocampus, Olfactory Bulb and Cerebellum.
Weingarten J, Laßek M, Mueller BF, Rohmer M, Baeumlisberger D, Beckert B, Ade J, Gogesch P, Acker-Palmer A, Karas M, Volknandt W PubMed
May 2015 Volume: 3 Issue: 2 Pages: 74-88

EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.
Nature communications
Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon SO, Segarra M, Eberhart CG, Acker-Palmer A, Tosato G PubMed
Mar 2015 Volume: 6 Issue: Pages: 6576

NTPDase2 and the P2Y1 receptor are not required for mammalian eye formation.
Purinergic signalling
Gampe K, Haverkamp S, Robson SC, Gachet C, Hüser L, Acker-Palmer A, Zimmermann H PubMed
Mar 2015 Volume: 11 Issue: 1 Pages: 155-60

Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.
Nature communications
Henze AT, Garvalov BK, Seidel S, Cuesta AM, Ritter M, Filatova A, Foss F, Dopeso H, Essmann CL, Maxwell PH, Reifenberger G, Carmeliet P, Acker-Palmer A, Acker T PubMed
Nov 2014 Volume: 5 Issue: Pages: 5582

PHD3 regulates EGFR internalization and signalling in tumours.
Nature communications
Garvalov BK, Foss F, Henze AT, Bethani I, Gräf-Höchst S, Singh D, Filatova A, Dopeso H, Seidel S, Damm M, Acker-Palmer A, Acker T PubMed
Nov 2014 Volume: 5 Issue: Pages: 5577

Amyloid precursor protein knockout diminishes synaptic vesicle proteins at the presynaptic active zone in mouse brain.
Current Alzheimer research
Laßek M, Weingarten J, Acker-Palmer A, Bajjalieh SM, Muller U, Volknandt W PubMed
2014 Volume: 11 Issue: 10 Pages: 971-80

FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.
Seiradake E, del Toro D, Nagel D, Cop F, Härtl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R PubMed
Oct 2014 Volume: 84 Issue: 2 Pages: 370-85

NTPDase2 and purinergic signaling control progenitor cell proliferation in neurogenic niches of the adult mouse brain.
Stem cells (Dayton, Ohio)
Gampe K, Stefani J, Hammer K, Brendel P, Pötzsch A, Enikolopov G, Enjyoji K, Acker-Palmer A, Robson SC, Zimmermann H PubMed
Jan 2015 Volume: 33 Issue: 1 Pages: 253-64

The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development.
Developmental cell
Geiger JC, Lipka J, Segura I, Hoyer S, Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC, Acker-Palmer A PubMed
Feb 2014 Volume: 28 Issue: 4 Pages: 381-93

Genetic dissection of plexin signaling in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Worzfeld T, Swiercz JM, Sentürk A, Genz B, Korostylev A, Deng S, Xia J, Hoshino M, Epstein JA, Chan AM, Vollmar B, Acker-Palmer A, Kuner R, Offermanns S PubMed
Feb 2014 Volume: 111 Issue: 6 Pages: 2194-9

Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system.
Development (Cambridge, England)
Bodea GO, Spille JH, Abe P, Andersson AS, Acker-Palmer A, Stumm R, Kubitscheck U, Blaess S PubMed
Feb 2014 Volume: 141 Issue: 3 Pages: 661-73

Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition.
The Journal of biological chemistry
Carrasco P, Sahún I, McDonald J, Ramírez S, Jacas J, Gratacós E, Sierra AY, Serra D, Herrero L, Acker-Palmer A, Hegardt FG, Dierssen M, Casals N PubMed
Jun 2012 Volume: 287 Issue: 25 Pages: 21224-32

Identification of testis 14-3-3 binding proteins by tandem affinity purification.
Puri P, Acker-Palmer A, Stahler R, Chen Y, Kline D, Vijayaraghavan S PubMed
Oct 2011 Volume: 1 Issue: 4 Pages: 354-365

Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia.
Acta neuropathologica
Doeppner TR, Bretschneider E, Doehring M, Segura I, Sentürk A, Acker-Palmer A, Hasan MR, ElAli A, Hermann DM, Bähr M PubMed
Oct 2011 Volume: 122 Issue: 4 Pages: 429-42

Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration.
Sentürk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A PubMed
Apr 2011 Volume: 472 Issue: 7343 Pages: 356-60

DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer.
Deutsch GB, Zielonka EM, Coutandin D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V PubMed
Feb 2011 Volume: 144 Issue: 4 Pages: 566-76

Preparation of retinal explant cultures to study ex vivo tip endothelial cell responses.
Nature protocols
Sawamiphak S, Ritter M, Acker-Palmer A PubMed
Sep 2010 Volume: 5 Issue: 10 Pages: 1659-65

Spatial organization of transmembrane receptor signalling.
The EMBO journal
Bethani I, Skånland SS, Dikic I, Acker-Palmer A PubMed
Aug 2010 Volume: 29 Issue: 16 Pages: 2677-88

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis.
Sawamiphak S, Seidel S, Essmann CL, Wilkinson GA, Pitulescu ME, Acker T, Acker-Palmer A PubMed
May 2010 Volume: 465 Issue: 7297 Pages: 487-91

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors.
Nature neuroscience
Essmann CL, Martinez E, Geiger JC, Zimmer M, Traut MH, Stein V, Klein R, Acker-Palmer A PubMed
Sep 2008 Volume: 11 Issue: 9 Pages: 1035-43

Phosphorylation-dependent interaction of tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein (YWHA) with PADI6 following oocyte maturation in mice.
Biology of reproduction
Snow AJ, Puri P, Acker-Palmer A, Bouwmeester T, Vijayaraghavan S, Kline D PubMed
Aug 2008 Volume: 79 Issue: 2 Pages: 337-47

Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation.
Nature neuroscience
Segura I, Essmann CL, Weinges S, Acker-Palmer A PubMed
Mar 2007 Volume: 10 Issue: 3 Pages: 301-10

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.
Molecular & cellular proteomics : MCP
Angrand PO, Segura I, Völkel P, Ghidelli S, Terry R, Brajenovic M, Vintersten K, Klein R, Superti-Furga G, Drewes G, Kuster B, Bouwmeester T, Acker-Palmer A PubMed
Dec 2006 Volume: 5 Issue: 12 Pages: 2211-27

Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation.
Circulation research
Bruhl T, Urbich C, Aicher D, Acker-Palmer A, Zeiher AM, Dimmeler S PubMed
Apr 2004 Volume: 94 Issue: 6 Pages: 743-51