Non-catalytic kinase functions
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Sebastian Mathea is obsessed with protein structures, no matter if it’s about catalytic mechanisms, substrate recognition or inhibitor binding modes.
Franziska Preuss is the rising star in the pseudokinase field. Gotta solve 'em all! In the end, there'll be a pattern, hopefully.
Deep Chatterjee is the 'King of Insect Cells'. His way of making challenging proteins is unexcelled in terms of yield and purity.
This is from collaboration with Benedikt Kessler's lab in Oxford. Profiling active DUBs in cells with a mass spec proteomics approach. We contributed making the ubiquitin probe! Full publication.
We just published a method paper about how to make recombinant protein kinases PMID 31267453.