Research Groups


Publications of Jasmin Hefendehl (Results: 12)


Microglia Phenotypes Converge in Aging and Neurodegenerative Disease.
Frontiers in neurology
Candlish M, Hefendehl JK PubMed
2021 Volume: 12 Issue: Pages: 660720

Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice.
Proceedings of the National Academy of Sciences of the United States of America
Degenhardt K, Wagner J, Skodras A, Candlish M, Koppelmann AJ, Wild K, Maxwell R, Rotermund C, von Zweydorf F, Gloeckner CJ, Davies HA, Madine J, Del Turco D, Feederle R, Lashley T, Deller T, Kahle P, Hefendehl JK, Jucker M, Neher JJ PubMed
09 2020 Volume: 117 Issue: 38 Pages: 23925-23931

Long-Term In Vivo Imaging of Individual Microglial Cells.
Methods in molecular biology (Clifton, N.J.)
Skodras AA, Hefendehl JK, Neher JJ PubMed
2019 Volume: 2034 Issue: Pages: 177-189

Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia.
Cell reports
Bernier LP, Bohlen CJ, York EM, Choi HB, Kamyabi A, Dissing-Olesen L, Hefendehl JK, Collins HY, Stevens B, Barres BA, MacVicar BA PubMed
06 2019 Volume: 27 Issue: 10 Pages: 2895-2908.e4

Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging.
Nature neuroscience
Füger P, Hefendehl JK, Veeraraghavalu K, Wendeln AC, Schlosser C, Obermüller U, Wegenast-Braun BM, Neher JJ, Martus P, Kohsaka S, Thunemann M, Feil R, Sisodia SS, Skodras A, Jucker M PubMed
Oct 2017 Volume: 20 Issue: 10 Pages: 1371-1376

Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging.
Nature communications
Hefendehl JK, LeDue J, Ko RW, Mahler J, Murphy TH, MacVicar BA PubMed
11 2016 Volume: 7 Issue: Pages: 13441

Activation of neuronal NMDA receptors triggers transient ATP-mediated microglial process outgrowth.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Dissing-Olesen L, LeDue JM, Rungta RL, Hefendehl JK, Choi HB, MacVicar BA PubMed
Aug 2014 Volume: 34 Issue: 32 Pages: 10511-27

Homeostatic and injury-induced microglia behavior in the aging brain.
Aging cell
Hefendehl JK, Neher JJ, Sühs RB, Kohsaka S, Skodras A, Jucker M PubMed
Feb 2014 Volume: 13 Issue: 1 Pages: 60-9

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".
Science (New York, N.Y.)
Veeraraghavalu K, Zhang C, Miller S, Hefendehl JK, Rajapaksha TW, Ulrich J, Jucker M, Holtzman DM, Tanzi RE, Vassar R, Sisodia SS PubMed
May 2013 Volume: 340 Issue: 6135 Pages: 924-f

Repeatable target localization for long-term in vivo imaging of mice with 2-photon microscopy.
Journal of neuroscience methods
Hefendehl JK, Milford D, Eicke D, Wegenast-Braun BM, Calhoun ME, Grathwohl SA, Jucker M, Liebig C PubMed
Apr 2012 Volume: 205 Issue: 2 Pages: 357-63

Long-term in vivo imaging of β-amyloid plaque appearance and growth in a mouse model of cerebral β-amyloidosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hefendehl JK, Wegenast-Braun BM, Liebig C, Eicke D, Milford D, Calhoun ME, Kohsaka S, Eichner M, Jucker M PubMed
Jan 2011 Volume: 31 Issue: 2 Pages: 624-9

Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
Coomaraswamy J, Kilger E, Wölfing H, Schäfer C, Kaeser SA, Wegenast-Braun BM, Hefendehl JK, Wolburg H, Mazzella M, Ghiso J, Goedert M, Akiyama H, Garcia-Sierra F, Wolfer DP, Mathews PM, Jucker M PubMed
Apr 2010 Volume: 107 Issue: 17 Pages: 7969-74