Members of the Protein Reaction Control Group
Prof. Dr. Martin Grininger
Lichtenberg (W1)-Professor of the Volkswagen Foundation &
Group Leader
Vice Director BMLS
Professor & Group Leader
Phone: +49 (0)69 798-42705
grininger(at)chemie.uni-frankfurt.de
Website
Martin was a project leader in the group of Prof. Dieter Oesterhelt at the Max Planck Institute of Biochemistry, Martinsried before he moved to Goethe University Frankfurt in 2012 as Lichtenberg Professor of the Volkswagen Foundation.
Curriculum Vitae | |
since June 2015 | Vice-Director Buchmann Institute for Molecular Life Sciences (BMLS) (Buchmann Institut für die molekularen Lebesnwissenschaften, Frankfurt am Main, Germany) |
since 2012 | Lichtenberg-Professor, Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Cluster of Excellence "Macromolecular Complexes", Goethe University Frankfurt |
2010-2011 | Guest Professor, University of Vienna, Faculty of Chemistry, Austria |
2006-2011 | Group Leader of project group "Biological Chemistry", Max-Planck-Institute of Biochemistry, Martinsried near Munich, Germany |
2002-2006 | PhD, Ludwig Maximilians University Munich, Germany |
2001-2002 | Diploma in Chemistry, Technical University Graz, Austria |
Awards and Fellowships | |
2014 | Preis für Exzellente Lehre am Fachbereich Biochemie, Chemie und Pharmazie der Goethe Universität Frankfurt |
2007 | Max-Planck-Institute of Biochemistry Junior Research Award |
2001 | Leonardo da Vinci Fellowship |
Publications |
Directed manipulation of a
flavoprotein photocycle. Staudt, H; Hoesl, MG; Dreuw, A;
Serdjukow, S; Oesterhelt, D; Budisa, N; Wachtveitl, J; Grininger, M; Angew Chem
Int Ed Engl, 2013 Aug PubMed
Structure and conformational variability of the mycobacterium tuberculosis fatty acid synthase multienzyme complex. Ciccarelli, L; Connell, SR; Enderle, M; Mills, DJ; Vonck, J; Grininger, M; Structure, 2013 Jul PubMed The flavoprotein dodecin as a redox probe for electron transfer through DNA. Yu, Y; Heidel, B; Parapugna, TL; Wenderhold-Reeb, S; Song, B; Schönherr, H; Grininger, M; Nöll, G; Angew Chem Int Ed Engl, 2013 Apr PubMed Mechanism of substrate shuttling by the acyl-carrier protein within the fatty acid mega-synthase. Anselmi, C; Grininger, M; Gipson, P; Faraldo-Gómez, JD; J Am Chem Soc, 2010 Sep PubMed Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase. Wende, A; Johansson, P; Vollrath, R; Dyall-Smith, M; Oesterhelt, D; Grininger, M; J Mol Biol, 2010 Jul PubMed Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy. Gipson, P; Mills, DJ; Wouts, R; Grininger, M; Vonck, J; Kühlbrandt, W; Proc Natl Acad Sci U S A, 2010 May PubMed Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase. Johansson, P; Mulinacci, B; Koestler, C; Vollrath, R; Oesterhelt, D; Grininger, M; Structure, 2009 Aug PubMed Blue-light-triggered photorelease of active chemicals captured by the flavoprotein dodecin. Nöll, G; Trawöger, S; von Sanden-Flohe, M; Dick, B; Grininger, M; Chembiochem, 2009 Mar PubMed Dodecin is the key player in flavin homeostasis of archaea. Grininger, M; Staudt, H; Johansson, P; Wachtveitl, J; Oesterhelt, D; J Biol Chem, 2009 May PubMed Dodecin sequesters FAD in closed conformation from the aqueous solution. Grininger, M; Seiler, F; Zeth, K; Oesterhelt, D; J Mol Biol, 2006 Dec PubMed Dodecins: a family of lumichrome binding proteins. Grininger, M; Zeth, K; Oesterhelt, D; J Mol Biol, 2006 Mar PubMed Parameters affecting the X-ray dose absorbed by macromolecular crystals. Murray, JW; Rudiño-Piñera, E; Owen, RL; Grininger, M; Ravelli, RB; Garman, EF; J Synchrotron Radiat, 2005 May PubMed Expression, crystallization and crystallographic analysis of DegS, a stress sensor of the bacterial periplasm. Grininger, M; Ravelli, RB; Heider, U; Zeth, K; Acta Crystallogr D Biol Crystallogr, 2004 Aug PubMed |
Administrative Assistant
Phone: +49 (0)69 798-46466
kasanzeva(at)em.uni.frankfurt.de
Nataliya helps us in administration and organization of the group.
Postdoctoral Fellow
Phone: +49 (0)69 798-42533
karthik.paithankar(at)chemie.uni-frankfurt.de
Dr.rer.nat from University of Leipzig. After a post-doc in the Garman group at the University of Oxford, he was a beamline scientist at BESSY II synchrotron at Helmholtz-Zentrum Berlin.
His favorite pastime is coding and learning natural languages.
Alexander Rittner
PhD Student
Phone: +49 (0)69 798-42533
rittner(at)chemie.uni-frankfurt.de
After studying biomedical chemistry until the "Vordiplom" in Mainz, Alex moved to Munich and did his bachelor's and master's degree in biochemistry at the Ludwig Maximilian University. His master's thesis was written in Zurich with Prof. Plückthun on G-protein coupled receptors. Alex joined the lab as a PhD student to work on the mammalian FAS, particularly on the human FAS.
PhD Student
Phone: +49 (0)69 798-42533
ma.fischer(at)chemie.uni-frankfurt.de
Manuel studied chemistry at the Goethe University of Frankfurt focused on organic synthesis. In his PhD thesis, Manuel evaluates new strategies for the inhibition of fatty acid synthases.
PhD Student
Phone: +49 (0)69 798-42533
csheil(at)stud.uni-frankfurt.de
Christina studied chemistry at the Goethe-University Frankfurt with a focus on chemical biology. During her master, she
performed structural studies on proteins at University of Tromsø. Her doctoral thesis involves conformational studies of
multi-functional proteins.
PhD Student
Phone: +49 (0)69 798-42533
bourdeaux(at)chemie.uni-frankfurt.de
Florian studied chemistry at the Goethe-University Frankfurt. During his bachelor, he focused on analytic and surface chemistry. Through his master, he switched to biochemistry and did a master thesis on Mycobacterium tuberculosis Dodecin. In his PhD, Florian is working on functional studies of large proteins.
PhD Student
Phone: +49 (0)69 798-42533
mklaus(at)stud.uni-frankfurt.de
Maja studied Life Science at the Leibniz University Hannover with a focus on molecular biology and chemistry of natural products with
a master's thesis from Stanford. In summer 2015, Maja joined the lab as a PhD student.